Diabetic Retinopathy finds “5G” compatibility

          Remote real time navigated retinal laser “tele- photocoagulation” in patients with severe non proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR) can be successfully undertaken with enhanced 5G high speed wireless system. The tele- laser intervention with 5G network, could save the rural patients from travelling a thousand miles […]

Role of Aflibercept in NonProliferative Diabetic Retinopathy (NPDR)

Intravitreal injections of aflibercept can reduce the severity of nonproliferative diabetic retinopathy, according to PANORAMA trials. The trial involved one eye in each of 402 participants with severe NPDR, randomized with one control group receiving sham injections or one of two aflibercept groups (the first group- aflibercept 2q16 receiving aflibercept 2 mg every 16 weeks […]

Dry Eye Disease and Pre-Operative Astigmatism

  Dry eye should be diagnosed and treated aggressively before undertaking cataract surgery as it may compromise pre surgical keratometric readings and visual outcomes. An estimated three quarters of eyes undergoing cataract surgery have astigmatism of more than 0.5D and one third have more than 1D. The unstable tear film affects the quality of optical […]

OCT Corneal Epithelial Mapping in Dry Eye Disease

Optical coherence tomography (OCT) corneal epithelial mapping is a new diagnostic tool with high sensitivity (86.4%) and specificity (91.7%) for screening and staging dry eye disease (DED) reliably and in a less invasive manner than the battery of tests in current practice. The best marker for diagnosing DED using OCT is superior intermediate epithelial thickness […]

SARS-CoV-2 and Ocular surface

  Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface. SARS-CoV-2 uses the angiotensin converting enzyme 2 (ACE2) as a receptor for cell entry, with transmembrane protease serine type 2 (TMPRSS2) responsible for cleaving the spike protein to fuse […]

Varenicline Nasal Spray Efficacious for Dry Eye

Experimental Phace III trial suggest, Varenicline is effective for Dry eye when squirted nasally. According to Dr Michael Raizman, MD, an associate professor of ophthalmology at Tufts University School of Medicine in Boston, Massachusetts, it stimulates trigeminal nerve nasally causing patient to sneeze and simultaneously eyes to tear. Unlike conventional dry eye treatment, Oyster Point’s […]

OCT-A and Amblyopia

  Optical coherence tomography(OCT-A) seems promising in diagnosing and understanding the pathogenesis of amblyopia, ideal in children, offering an objective tool on top of visual acuity to guide treatment plans. A population based cohort study (30 children with amblyopia and 1045 controls) confirms the presence of retinal microvasculature abnormalities in amblyopic eyes, which opens the […]

Young Myopes and Atropine – Treat Them Right

  With COVID-19 pandemic outbreak and reduced outdoor time for children, the risk for childhood myopia has increased many folds. Young children (around 6 years of age) require higher concentrations (0.05%) of atropine to achieve similar reductions in myopia progression as older children (8-10 years of age) on lower concentrations (0.025% or 0.01%), since myopia […]

Enteral Lipid Supplementation and Retinopathy of Prematurity

Enteral lipid supplementation with arachidonic acid (AA, 100 mg/kg/day) and docosahexaenoic acid (DHA, 50 mg/kg/day) in a ratio of 2:1 starting within three days of birth to premature infants born before 27 months reduces the risk of severe retinopathy of prematurity (ROP) to half as compared to infants without supplementation when treated till 40 weeks […]

Drug Abuse and Endophthalmitis

A U.S based study suggests a “high degree of suspicion” in patients with drug abuse leading to endogenous endophthalmitis as high as up to four folds, especially to recent trend of consuming intravenous opiates such as heroin. The morbidity and mortality rates from endogenous endophthalmitis worsens more with comorbidities like diabetes, malignancy, chronic kidney disease, Chronic […]